ptp-3

Caenorhabditis elegans

Enables protein tyrosine phosphatase activity. Involved in several processes, including embryonic morphogenesis; nervous system development; and neuroblast migration. Located in adherens junction and synapse. Expressed in embryonic cell; hypodermis; and nervous system. Human ortholog(s) of this gene implicated in artery disease (multiple); glucose metabolism disease (multiple); and obesity. Is an ortholog of human PTPRD (protein tyrosine phosphatase receptor type D) and PTPRF (protein tyrosine phosphatase receptor type F).

ZK856.5

Caenorhabditis elegans

Predicted to enable phosphoric diester hydrolase activity. Predicted to be located in extracellular space. Is an ortholog of human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B).

ptp-2

Caenorhabditis elegans

Predicted to enable non-membrane spanning protein tyrosine phosphatase activity and phosphotyrosine residue binding activity. Involved in several processes, including nematode larval development; positive regulation of signal transduction; and positive regulation of vulval development. Located in cytoplasmic vesicle. Expressed in body wall musculature; head ganglion; pharynx; spermatheca; and tail. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 1; Noonan syndrome with multiple lentigines 1; and anogenital venereal wart. Is an ortholog of human PTPN6 (protein tyrosine phosphatase non-receptor type 6).

prel-3

Caenorhabditis elegans

Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human PRELID3B (PRELI domain containing 3B).

ptp-1

Caenorhabditis elegans

Predicted to enable protein tyrosine phosphatase activity. Located in sarcoplasmic reticulum. Expressed in muscle cell; nerve ring; neurons; pharyngeal nervous system; and ventral nerve cord. Is an ortholog of human PTPN3 (protein tyrosine phosphatase non-receptor type 3) and PTPN4 (protein tyrosine phosphatase non-receptor type 4).

C44H4.4

Caenorhabditis elegans

Expressed in head. Is an ortholog of human BLTP3A (bridge-like lipid transfer protein family member 3A) and BLTP3B (bridge-like lipid transfer protein family member 3B). Human BLTP3B enables GARP complex binding activity; lipid transfer activity; and protein homodimerization activity.

sftb-6

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Is an ortholog of human SF3B6 (splicing factor 3b subunit 6).

teg-4

Caenorhabditis elegans

Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP. Is an ortholog of human SF3B3 (splicing factor 3b subunit 3).

H18N23.2

Caenorhabditis elegans

Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to be part of protein phosphatase type 1 complex. Is an ortholog of human PPP1R3B (protein phosphatase 1 regulatory subunit 3B).

sftb-2

Caenorhabditis elegans

Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in Goldenhar syndrome. Is an ortholog of human SF3B2 (splicing factor 3b subunit 2).