prdx-2

Caenorhabditis elegans

Enables thioredoxin peroxidase activity. Involved in several processes, including determination of adult lifespan; positive regulation of brood size; and response to stress. Located in cytoplasm. Expressed in body wall musculature; corpus; gonad; head; and tail. Human ortholog(s) of this gene implicated in colorectal cancer; methylmalonic aciduria and homocystinuria type cblC; and oral squamous cell carcinoma. Is an ortholog of human PRDX1 (peroxiredoxin 1) and PRDX2 (peroxiredoxin 2).

prdx-3

Caenorhabditis elegans

Predicted to enable thioredoxin peroxidase activity. Predicted to be involved in cell redox homeostasis; hydrogen peroxide catabolic process; and response to oxidative stress. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 32. Is an ortholog of human PRDX3 (peroxiredoxin 3).