Enables cohesin loader activity. Involved in several processes, including chromosome organization; double-strand break repair involved in meiotic recombination; and regulation of cell cycle process. Located in chromosome and nucleus. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 1. Is an ortholog of human NIPBL (NIPBL cohesin loading factor).
Predicted to enable double-stranded DNA binding activity. Involved in anterior/posterior axon guidance; dorsal/ventral axon guidance; and egg-laying behavior. Located in axon and cytoplasm. Expressed in nervous system; oocyte; and vulval muscle. Is an ortholog of human MAU2 (MAU2 sister chromatid cohesion factor).
Predicted to enable chitin binding activity. Involved in endoplasmic reticulum unfolded protein response. Predicted to be located in extracellular region.
Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by pqn-59 based on proteomic studies. Is affected by rifampin based on RNA-seq studies.