- myrf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in ecdysis, collagen and cuticulin-based cuticle and nematode larval development. Located in basal part of cell and endoplasmic reticulum. Expressed in several structures, including ciliated neurons; excretory duct; gonad; pharyngeal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; and eye disease (multiple). Is an ortholog of human MYRFL (myelin regulatory factor like).
- egl-47 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and egg-laying behavior. Predicted to be located in axon; membrane; and somatodendritic compartment. Expressed in HSNL; HSNR; PVQL; PVQR; and vulva.
- scc-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cohesin loader activity. Involved in several processes, including chromosome organization; double-strand break repair involved in meiotic recombination; and regulation of cell cycle process. Located in chromosome and nucleus. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 1. Is an ortholog of human NIPBL (NIPBL cohesin loading factor).