ppm-1.A

Caenorhabditis elegans

Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of stress-activated MAPK cascade. Predicted to be located in cytosol and nucleus. Is an ortholog of human PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A) and PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B).

ppm-1.H

Caenorhabditis elegans

Predicted to enable [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity. Predicted to be located in mitochondrion. Is an ortholog of human PPM1J (protein phosphatase, Mg2+/Mn2+ dependent 1J).

ppm-1.D

Caenorhabditis elegans

Predicted to enable mitogen-activated protein kinase binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of gene expression, epigenetic. Predicted to be located in cytosol and nucleus. Expressed in distal tip cell and germline blastomere. Human ortholog(s) of this gene implicated in breast cancer and pre-malignant neoplasm. Is an ortholog of human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D).

ppm-1.G

Caenorhabditis elegans

Predicted to enable metal ion binding activity and myosin phosphatase activity. Expressed in gonad and head. Is an ortholog of human PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G).

F59E12.17

Caenorhabditis elegans

Enriched in intestine and neurons based on microarray studies. Is affected by several genes including nuo-6; ppm-1.D; and inx-14 based on RNA-seq; proteomic; and microarray studies. Is affected by Hydrolyzable Tannins based on microarray studies.

T23B3.1

Caenorhabditis elegans

Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including srbc-48; spr-1; and ppm-1.D based on RNA-seq; microarray; and proteomic studies. Is affected by four chemicals including Zidovudine; paraquat; and Cisplatin based on RNA-seq and microarray studies.

irld-65

Caenorhabditis elegans

Enriched in amphid sheath cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including etr-1; csr-1; and ppm-1.D based on RNA-seq; microarray; and proteomic studies. Is affected by Sodium Chloride and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L domain; Receptor L-domain; SPS2 domain-containing protein; and Receptor L-domain superfamily.

F26F4.12

Caenorhabditis elegans

Enriched in germ line and intestine based on RNA-seq and microarray studies. Is affected by several genes including ppm-1.D; inx-14; and jmjd-3.1 based on proteomic; RNA-seq; and microarray studies. Is affected by nine chemicals including rotenone; bisphenol S; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ankyrin repeat-containing domain superfamily; Ankyrin repeat domain-containing protein 49; Ankyrin repeats (3 copies); and Ankyrin repeat. Is an ortholog of human ANKRD49 (ankyrin repeat domain 49).

urb-1

Caenorhabditis elegans

Enriched in several structures, including ABalpapppa; ABarapappa; ABplpppapa; ABprpppapa; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including nuo-6; mrg-1; and ppm-1.D based on RNA-seq; proteomic; and microarray studies. Is affected by fourteen chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Nucleolar pre-ribosomal-associated protein 1, C-terminal domain; Armadillo-type fold; Armadillo-like helical; and Nucleolar pre-ribosomal-associated protein 1. Is an ortholog of human URB1 (URB1 ribosome biogenesis homolog). Human URB1 enables RNA binding activity.

srlf-31

Caenorhabditis elegans

Enriched in several structures, including accessory cell; germ line; hermaphrodite somatic gonadal cell; neurons; and pharyngeal gland cell based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including etr-1; hsf-1; and ppm-1.D based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, metal-binding domain; SXP/RAL-2 family protein Ani s 5-like, cation-binding domain; and SXP/RAL-2-related.