Bma-dpy-2

Brugia malayi

Predicted to be a structural constituent of cuticle. Is an ortholog of C. elegans dpy-2. In C. elegans, dpy-2 is involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and regulation of growth.

Bma-nrde-2

Brugia malayi

Enriched in reproductive tract based on proteomic studies. Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: siRNA-mediated silencing protein NRDE-2 and NRDE-2, necessary for RNA interference. Is an ortholog of C. elegans nrde-2. In C. elegans, nrde-2 is involved in regulatory ncRNA-mediated heterochromatin formation and regulatory ncRNA-mediated post-transcriptional gene silencing.

Bm10166

Brugia malayi

Predicted to enable ATP binding activity and nucleic acid binding activity. Is an ortholog of C. elegans glh-1; glh-2; and glh-3. In C. elegans, glh-1 is involved in germ cell development and post-embryonic development.

Bma-haf-2

Brugia malayi

Predicted to enable ABC-type peptide transporter activity; ATP binding activity; and ATP hydrolysis activity. Predicted to be involved in peptide transport and transmembrane transport. Predicted to be located in lysosomal membrane. Is an ortholog of C. elegans haf-2. In C. elegans, haf-2 is involved in regulatory ncRNA-mediated post-transcriptional gene silencing.

Bm3605

Brugia malayi

Predicted to enable RNA-dependent RNA polymerase activity. Is an ortholog of C. elegans ego-1; rrf-1; and rrf-2. In C. elegans, ego-1 is involved in gamete generation; nuclear pore localization; and regulatory ncRNA-mediated post-transcriptional gene silencing.

Bm5059

Brugia malayi

Predicted to enable RNA-dependent RNA polymerase activity. Is an ortholog of C. elegans ego-1; rrf-1; and rrf-2. In C. elegans, ego-1 is involved in gamete generation; nuclear pore localization; and regulatory ncRNA-mediated post-transcriptional gene silencing.

Bm4985

Brugia malayi

Predicted to enable nucleic acid binding activity; nucleotidyltransferase activity; and zinc ion binding activity. Is an ortholog of C. elegans Y34F4.3; T08B2.4; and R07H5.11. In C. elegans, mut-2 is involved in embryo development; meiotic chromosome segregation; and regulatory ncRNA-mediated post-transcriptional gene silencing.

Bma-tbcc-1

Brugia malayi

Predicted to be involved in post-chaperonin tubulin folding pathway. Is an ortholog of C. elegans tbcc-1.

Bma-tbca-1

Brugia malayi

Predicted to enable beta-tubulin binding activity. Predicted to be involved in post-chaperonin tubulin folding pathway and tubulin complex assembly. Is an ortholog of C. elegans tbca-1.

Bma-ceh-32

Brugia malayi

Predicted to enable DNA binding activity. Is an ortholog of C. elegans ceh-32. In C. elegans, ceh-32 is involved in neuron differentiation and post-embryonic animal morphogenesis.