Predicted to enable phosphatidylinositol phospholipase C activity. Predicted to be involved in phosphatidylinositol metabolic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol.
Predicted to enable phosphatidylinositol phospholipase C activity. Involved in sleep. Predicted to be located in ruffle membrane. Expressed in ALA; gonad; intestine; and non-striated muscle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); familial adenomatous polyposis; and familial cold autoinflammatory syndrome 3. Is an ortholog of human PLCG2 (phospholipase C gamma 2).
Predicted to enable phosphatidylinositol phospholipase C activity. Predicted to be involved in phosphatidylinositol metabolic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Expressed in vas deferens. Human ortholog(s) of this gene implicated in Alzheimer's disease; nonsyndromic congenital nail disorder 3; and spermatogenic failure 17. Is an ortholog of human PLCD3 (phospholipase C delta 3).
Predicted to enable mRNA binding activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and response to stress. Located in P granule and P-body. Expressed in head; motor neurons; neurons; tail; and touch receptor neurons. Is an ortholog of human DCP1A (decapping mRNA 1A) and DCP1B (decapping mRNA 1B).
Enables GTPase inhibitor activity; phosphatidylinositol phospholipase C activity; and small GTPase binding activity. Involved in several processes, including 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process; defense response to Gram-positive bacterium; and positive regulation of protein import into nucleus. Expressed in excretory system; intestine; neurons; spermatheca; and vulva. Human ortholog(s) of this gene implicated in gastric adenocarcinoma; nephrotic syndrome type 2; and nephrotic syndrome type 3. Is an ortholog of human PLCE1 (phospholipase C epsilon 1).
Predicted to enable D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in antifungal innate immune response and positive regulation of gene expression. Located in cytoplasm and nucleus. Expressed in several structures, including excretory cell; intestine; nerve ring; neurons; and pharynx. Is an ortholog of human GNA12 (G protein subunit alpha 12) and GNA13 (G protein subunit alpha 13).
Predicted to enable serine-type endopeptidase inhibitor activity. Involved in spermatid development. Located in extracellular space and secretory vesicle. Expressed in body wall musculature; coelomocyte; reproductive tract; and in male.