Predicted to enable mRNA binding activity. Predicted to be involved in nervous system development and regulation of alternative mRNA splicing, via spliceosome. Located in P granule. Expressed in several structures, including D; Psub4; Z2; Z3; and germ line.
Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity and 1-phosphatidylinositol-5-phosphate 4-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to be located in plasma membrane. Is an ortholog of human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha).
Predicted to enable phospholipid binding activity and phospholipid transporter activity. Predicted to be involved in intermembrane lipid transfer and phospholipid transport. Located in ciliary transition zone and synapse. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in cone-rod dystrophy 5. Is an ortholog of human PITPNM1 (phosphatidylinositol transfer protein membrane associated 1).
Predicted to enable DNA-directed DNA polymerase activity. Involved in embryo development; error-prone translesion synthesis; and negative regulation of mitotic DNA damage checkpoint. Located in nucleus. Human ortholog(s) of this gene implicated in female breast cancer and xeroderma pigmentosum variant type. Is an ortholog of human POLH (DNA polymerase eta).