Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including etr-1; ilc-17.1; and pie-1 based on RNA-seq studies.
Predicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; formation of primary germ layer; and negative regulation of macromolecule metabolic process. Located in several cellular components, including P granule; centrosome; and cytosol. Expressed in germ line; head muscle; and nerve ring.
Enriched in intestine based on microarray studies. Is affected by several genes including pie-1; sir-2.1; and lin-14 based on RNA-seq and microarray studies. Is affected by Cholestanol based on microarray studies.
Enables protein serine/threonine kinase activity and protein tyrosine kinase activity. Involved in several processes, including P granule disassembly; asymmetric protein localization involved in cell fate determination; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in cell cortex and intracellular non-membrane-bounded organelle. Expressed in several structures, including body wall musculature; embryonic cell; gonad; oocyte; and pharynx. Used to study Down syndrome. Is an ortholog of human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) and DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3).
Enables chitin binding activity. Involved in several processes, including eggshell formation; mitotic cytokinesis; and regulation of cytokinesis. Located in external encapsulating structure and perivitelline space. Expressed in eggshell.
Predicted to enable DNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of alpha DNA polymerase:primase complex. Expressed in gonad; vulva; and vulval precursor cell. Is an ortholog of human POLA2 (DNA polymerase alpha 2, accessory subunit).
Predicted to enable glucosamine 6-phosphate N-acetyltransferase activity. Involved in chitin biosynthetic process and eggshell formation. Predicted to be located in Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment; and late endosome. Is an ortholog of human GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1).
Predicted to enable chitin synthase activity. Involved in chitin biosynthetic process; eggshell formation; and positive regulation of protein localization to cell cortex. Located in cell cortex and plasma membrane. Expressed in Psub1.