Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including etr-1; ilc-17.1; and pie-1 based on RNA-seq studies.
Predicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; formation of primary germ layer; and negative regulation of macromolecule metabolic process. Located in several cellular components, including P granule; centrosome; and cytosol. Expressed in germ line; head muscle; and nerve ring.
Enriched in intestine based on microarray studies. Is affected by several genes including pie-1; sir-2.1; and lin-14 based on RNA-seq and microarray studies. Is affected by Cholestanol based on microarray studies.
Predicted to enable nucleic acid binding activity. Predicted to be involved in regulation of gene expression. Located in endoplasmic reticulum. Expressed in germ cell; germ line; pharynx; and somatic cell. Is an ortholog of human YBX3 (Y-box binding protein 3).
Enables mRNA 3'-UTR binding activity; protein domain specific binding activity; and protein kinase binding activity. Involved in regulation of protein localization. Located in P granule. Expressed in AB; ABa; ABp; and germ line.
Predicted to enable DNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of alpha DNA polymerase:primase complex. Expressed in gonad; vulva; and vulval precursor cell. Is an ortholog of human POLA2 (DNA polymerase alpha 2, accessory subunit).
Predicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; establishment of cell polarity; and formation of primary germ layer. Located in P granule. Expressed in germ line.
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed in embryonic cell. Is an ortholog of human AQR (aquarius intron-binding spliceosomal factor).
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in mitotic sister chromatid segregation. Located in condensed chromosome and nucleus.
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in embryonic digestive tract morphogenesis; negative regulation of transcription by RNA polymerase II; and negative regulation of vulval development. Part of RNA polymerase II transcription repressor complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; gonad; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Sifrim-Hitz-Weiss syndrome; gastrointestinal system cancer (multiple); and lung adenocarcinoma. Is an ortholog of human CHD3 (chromodomain helicase DNA binding protein 3).