Enables calmodulin-dependent protein kinase activity; identical protein binding activity; and transmembrane transporter binding activity. Involved in MAPK cascade; medium-term memory; and positive regulation of gene expression. Acts upstream of or within serotonin biosynthetic process. Located in axon cytoplasm. Expressed in several structures, including AWC; copulatory spicule; gonadal sheath cell; postcloacal sensillum; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; intellectual disability (multiple); and malignant astrocytoma. Is an ortholog of human CAMK2D (calcium/calmodulin dependent protein kinase II delta).
Is affected by several genes including etr-1; eri-1; and egl-43 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine; fluoranthene; and paraquat based on microarray studies.
Is affected by several genes including kri-1; unc-70; and egl-43 based on RNA-seq studies. Is affected by four chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq studies.