Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Is an ortholog of human PGC (progastricsin).
Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in Alzheimer's disease and frontotemporal dementia. Is an ortholog of human BACE1 (beta-secretase 1); BACE2 (beta-secretase 2); and PGC (progastricsin).
Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human PGC (progastricsin) and REN (renin).
Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Located in cytoplasm and external side of apical plasma membrane. Expressed in intestinal cell and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human PGC (progastricsin) and REN (renin).
Involved in several processes, including protein localization to euchromatin; regulation of gene expression; and sexual reproduction. Located in autosome. Part of euchromatin. Expressed in several structures, including Caa; Cpa; Ea; Psub4; and somatic cell. Is an ortholog of human MORF4L2 (mortality factor 4 like 2).