Predicted to enable ATP hydrolysis activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Is an ortholog of human PEX1 (peroxisomal biogenesis factor 1).
Enables protein kinase activity. Involved in several processes, including Ras protein signal transduction; nematode male tail tip morphogenesis; and positive regulation of vulval development. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Is an ortholog of human KSR1 (kinase suppressor of ras 1) and KSR2 (kinase suppressor of ras 2).
Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Is an ortholog of human KEL (Kell metallo-endopeptidase (Kell blood group)).
Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Expressed in RIH and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); congestive heart failure; and dilated cardiomyopathy. Is an ortholog of human ECE1 (endothelin converting enzyme 1).
Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); congestive heart failure; and dilated cardiomyopathy. Is an ortholog of human ECE1 (endothelin converting enzyme 1).
Predicted to enable metalloendopeptidase activity. Involved in olfactory learning and regulation of chemotaxis. Located in cell surface. Expressed in GLR and body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2T; X-linked dominant hypophosphatemic rickets; and cerebellar ataxia type 43. Is an ortholog of human MME (membrane metalloendopeptidase) and MMEL1 (membrane metalloendopeptidase like 1).