mrp-6

Caenorhabditis elegans

Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human ABCC4 (ATP binding cassette subfamily C member 4 (PEL blood group)).

aman-3

Caenorhabditis elegans

Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Predicted to be located in Golgi membrane.

rpb-3

Caenorhabditis elegans

Predicted to enable DNA-directed 5'-3' RNA polymerase activity and protein dimerization activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2C (RNA polymerase II subunit C).

aptf-3

Caenorhabditis elegans

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and regulation of cell population proliferation. Predicted to be located in nucleus. Expressed in head neurons and intestine.

rpb-2

Caenorhabditis elegans

Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and small molecule binding activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II, core complex. Expressed in head and tail. Is an ortholog of human POLR2B (RNA polymerase II subunit B).

mel-3

Caenorhabditis elegans

Acts upstream of or within embryo development.

gls-1

Caenorhabditis elegans

Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in mRNA 3'-end processing. Located in P granule. Expressed in germ line.

mec-3

Caenorhabditis elegans

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and transcription coactivator activity. Involved in several processes, including mechanosensory behavior; neuron projection organization; and positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Expressed in VA neuron; touch receptor neurons; ventral nerve cord; and vulva. Is an ortholog of human LHX1 (LIM homeobox 1) and LHX5 (LIM homeobox 5).

rpb-9

Caenorhabditis elegans

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II; transcription initiation at RNA polymerase II promoter; and transcription-coupled nucleotide-excision repair. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2I (RNA polymerase II subunit I).

gei-3

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 45. Is an ortholog of human CIC (capicua transcriptional repressor).