pas-7

Caenorhabditis elegans

Enables identical protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Located in cytoplasm and nucleus. Is an ortholog of human PSMA3 (proteasome 20S subunit alpha 3).

pas-5

Caenorhabditis elegans

Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Expressed in body wall musculature; germ line; gonad; hypodermis; and vulva. Is an ortholog of human PSMA5 (proteasome 20S subunit alpha 5).

pas-4

Caenorhabditis elegans

Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Expressed in tail. Is an ortholog of human PSMA7 (proteasome 20S subunit alpha 7) and PSMA8 (proteasome 20S subunit alpha 8).

pas-6

Caenorhabditis elegans

Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Is an ortholog of human PSMA1 (proteasome 20S subunit alpha 1).

pas-1

Caenorhabditis elegans

Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Human ortholog(s) of this gene implicated in myocardial infarction. Is an ortholog of human PSMA6 (proteasome 20S subunit alpha 6).

vacl-14

Caenorhabditis elegans

Predicted to be involved in phosphatidylinositol biosynthetic process. Predicted to be located in endosome membrane. Predicted to be part of PAS complex. Human ortholog(s) of this gene implicated in striatonigral degeneration. Is an ortholog of human VAC14 (VAC14 component of PIKFYVE complex).

cky-1

Caenorhabditis elegans

Contributes to sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Expressed in pharyngeal cell. Is an ortholog of human NPAS4 (neuronal PAS domain protein 4).

pas-3

Caenorhabditis elegans

Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Is an ortholog of human PSMA4 (proteasome 20S subunit alpha 4).

lin-42

Caenorhabditis elegans

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of dauer larval development; negative regulation of miRNA transcription; and regulation of development, heterochronic. Located in cytoplasm and nucleus. Expressed in head; hyp7 syncytium; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome 1 and cocaine dependence. Is an ortholog of human PER1 (period circadian regulator 1) and PER2 (period circadian regulator 2).

pas-2

Caenorhabditis elegans

Enables identical protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Is an ortholog of human PSMA2 (proteasome 20S subunit alpha 2).