oma-2

Caenorhabditis elegans

Enables mRNA regulatory element binding translation repressor activity. Involved in several processes, including meiotic nuclear membrane disassembly; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Expressed in several structures, including germ line; head muscle; intestine; oocyte; and somatic nervous system. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2).

oma-1

Caenorhabditis elegans

Enables mRNA 3'-UTR AU-rich region binding activity and mRNA regulatory element binding translation repressor activity. Involved in several processes, including meiotic nuclear membrane disassembly; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Expressed in several structures, including head muscle; intestine; neurons; somatic nervous system; and vulva. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2).

pfd-2

Caenorhabditis elegans

Predicted to enable protein folding chaperone. Predicted to be involved in protein folding. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human PFDN2 (prefoldin subunit 2).

moe-3

Caenorhabditis elegans

Predicted to enable mRNA binding activity and metal ion binding activity. Predicted to be involved in negative regulation of gene expression. Expressed in coelomocyte; gonad; intestine; neurons; and ventral nerve cord. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2).

sid-2

Caenorhabditis elegans

Involved in RNA transport and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in apical plasma membrane and cytoplasm. Expressed in ciliated neurons; excretory duct; intestine; and in male.

rde-3

Caenorhabditis elegans

Predicted to enable poly(A) RNA polymerase activity. Involved in embryo development; meiotic chromosome segregation; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in mutator focus. Expressed in germ line.

rrf-2

Caenorhabditis elegans

Predicted to enable RNA-dependent RNA polymerase activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be part of nuclear RNA-directed RNA polymerase complex.

glb-2

Caenorhabditis elegans

Predicted to enable heme binding activity and oxygen binding activity. Expressed in head neurons.

cls-2

Caenorhabditis elegans

Predicted to enable microtubule binding activity. Involved in several processes, including cytoplasmic streaming; microtubule cytoskeleton organization; and nuclear chromosome segregation. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Expressed in embryonic cell. Is an ortholog of human CLASP2 (cytoplasmic linker associated protein 2).

vha-2

Caenorhabditis elegans

Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in programmed cell death and proton transmembrane transport. Predicted to be located in membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Expressed in excretory cell and rectum. Human ortholog(s) of this gene implicated in early-onset epilepsy 3 and thyroid gland carcinoma. Is an ortholog of human ATP6V0C (ATPase H+ transporting V0 subunit c).