Predicted to enable NADH dehydrogenase (ubiquinone) activity and small molecule binding activity. Involved in several processes, including dauer exit; determination of adult lifespan; and inductive cell migration. Located in mitochondrion. Used to study mitochondrial complex I deficiency. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 4. Is an ortholog of human NDUFV1 (NADH:ubiquinone oxidoreductase core subunit V1).
Is affected by tdp-1; nhr-25; and nuo-6 based on microarray studies. Is affected by Atrazine; fluoranthene; and Microcystin-LR based on microarray studies.