olrn-1

Caenorhabditis elegans

Involved in olfactory learning. Predicted to be located in plasma membrane. Expressed in head neurons; pharyngeal cell; and rectal gland cell.

nsy-4

Caenorhabditis elegans

Enables calcium channel inhibitor activity and protein kinase inhibitor activity. Involved in determination of left/right asymmetry in nervous system. Located in plasma membrane and plasma membrane bounded cell projection. Expressed in anterior hypodermis; blast cell; excretory cell; neurons; and tail hypodermis.

nsy-7

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Involved in determination of left/right asymmetry in nervous system and negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in amphid sheath cell; intestine; and neurons.

nsy-1

Caenorhabditis elegans

Enables MAP kinase kinase kinase activity; mitogen-activated protein kinase kinase binding activity; and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including determination of adult lifespan; positive regulation of macromolecule biosynthetic process; and response to stress. Located in axon cytoplasm; neuronal cell body; and postsynaptic density. Expressed in head; rectal gland cell; and tail. Used to study amphetamine abuse. Human ortholog(s) of this gene implicated in Huntington's disease and perinatal necrotizing enterocolitis. Is an ortholog of human MAP3K5 (mitogen-activated protein kinase kinase kinase 5).

mau-6

Caenorhabditis elegans

let-6

Caenorhabditis elegans

Acts upstream of or within nematode larval development.

amo-6

Caenorhabditis elegans

cps-6

Caenorhabditis elegans

Enables endonuclease activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Located in mitochondrial intermembrane space. Is an ortholog of human ENDOG (endonuclease G).

Y57G11C.3

Caenorhabditis elegans

Predicted to enable 6-phosphogluconolactonase activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Located in nucleus. Expressed in germ cell. Is an ortholog of human PGLS (6-phosphogluconolactonase).

glb-6

Caenorhabditis elegans

Enables heme binding activity; iron ion binding activity; and oxygen binding activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in neurons and somatic nervous system.