Contributes to intracellularly cGMP-activated cation channel activity. Involved in several processes, including G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; positive regulation of macromolecule biosynthetic process; and thermosensory behavior. Part of cation channel complex. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in achromatopsia 3 and retinitis pigmentosa 45. Is an ortholog of human CNGB1 (cyclic nucleotide gated channel subunit beta 1) and CNGB3 (cyclic nucleotide gated channel subunit beta 3).
Enables phosphatidylserine binding activity. Involved in lipid transport and positive regulation of engulfment of apoptotic cell. Located in extracellular region. Expressed in apoptotic cell; body wall musculature; intestine; and pharyngeal cell.
Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups and lipid binding activity. Predicted to be involved in lipid transport. Predicted to be located in membrane. Expressed in hyp3; hyp5; and intestine.
Enables peroxidase activity. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle; nematode larval development; and post-embryonic body morphogenesis. Predicted to be located in extracellular space. Expressed in anterior hypodermis and hypodermal cell.
Predicted to enable 7-dehydrocholesterol reductase activity. Predicted to be involved in brassinosteroid biosynthetic process and cholesterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in several diseases, including Greenberg dysplasia; Pelger-Huet anomaly; and autoimmune disease (multiple). Is an ortholog of human DHCR7 (7-dehydrocholesterol reductase).