nrde-1

Caenorhabditis elegans

Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in nucleus.

nrde-4

Caenorhabditis elegans

Involved in regulatory ncRNA-mediated post-transcriptional gene silencing.

rrp-8

Caenorhabditis elegans

Predicted to enable methylated histone binding activity. Predicted to be involved in cellular response to glucose starvation; rDNA heterochromatin formation; and regulation of transcription by glucose. Predicted to be located in nucleolus. Predicted to be part of chromatin silencing complex and rDNA heterochromatin. Expressed widely. Is an ortholog of human RRP8 (ribosomal RNA processing 8).

nrde-2

Caenorhabditis elegans

Involved in regulatory ncRNA-mediated heterochromatin formation and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in nucleus. Expressed widely. Is an ortholog of human NRDE2 (NRDE-2, necessary for RNA interference, domain containing).

nrde-3

Caenorhabditis elegans

Enables siRNA binding activity. Involved in RNA import into nucleus; olfactory learning; and regulation of gene expression. Located in nucleus. Part of RNAi effector complex. Expressed in several structures, including AWC; gonad; hypodermis; pharynx; and vulva.

mau-8

Caenorhabditis elegans

Expressed in body wall musculature; germ line; hypodermis; intestine; and pharynx. Is an ortholog of human PDC (phosducin) and PDCL (phosducin like).

Y48B6A.17

Caenorhabditis elegans

Is affected by several genes including puf-8; npr-8; and ins-11 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies.

set-8

Caenorhabditis elegans

Predicted to enable double-stranded DNA binding activity and histone methyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus.

Y49F6B.20

Caenorhabditis elegans

Is affected by nhr-8 based on RNA-seq studies.

F19B6.9

Caenorhabditis elegans

Is affected by npr-8 based on RNA-seq studies.