Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cell fate specification; muscle cell differentiation; and regulation of gene expression. Acts upstream of or within lipid homeostasis. Located in nucleus. Part of chromatin. Expressed in several structures, including body wall musculature; neurons; reproductive system; ventral nerve cord; and vulval precursor cell. Used to study leukemia and restless legs syndrome. Human ortholog(s) of this gene implicated in several diseases, including cleft palate; cleft palate, cardiac defects, and intellectual disabillity; and open-angle glaucoma. Is an ortholog of human MEIS1 (Meis homeobox 1).
Enables sequence-specific DNA binding activity. Involved in several processes, including nematode male tail tip morphogenesis; pattern specification process; and positive regulation of miRNA transcription. Located in nucleus. Expressed in head muscle; intestine; linker cell; somatic nervous system; and tail. Is an ortholog of several human genes including HOXA9 (homeobox A9); HOXB9 (homeobox B9); and HOXC10 (homeobox C10).
Enables transcription coactivator binding activity. Involved in regulation of asymmetric cell division. Located in nucleus. Expressed in several structures, including TL.aa; TL.pa; TR.aa; TR.pa; and hypodermal cell.
Predicted to enable inositol-polyphosphate 5-phosphatase activity. Expressed in pharyngeal muscle cell and rectal epithelium. Is an ortholog of human INPP5A (inositol polyphosphate-5-phosphatase A).
Enables GTPase activating protein binding activity. Involved in molting cycle. Is an ortholog of human RABEP1 (rabaptin, RAB GTPase binding effector protein 1).
Predicted to enable inositol-polyphosphate 5-phosphatase activity. Involved in negative regulation of epidermal growth factor receptor signaling pathway and ovulation. Expressed in spermatheca. Is an ortholog of human INPP5A (inositol polyphosphate-5-phosphatase A).