Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell fate commitment; embryonic pattern specification; and positive regulation of DNA-templated transcription. Located in condensed nuclear chromosome. Expressed in several structures, including ABprpppppaa; Caaaaa; enteric muscle; epithelial cell; and tail spike. Human ortholog(s) of this gene implicated in Barrett's esophagus. Is an ortholog of human CDX1 (caudal type homeobox 1) and CDX2 (caudal type homeobox 2).
Enables sequence-specific DNA binding activity. Involved in several processes, including nematode male tail tip morphogenesis; pattern specification process; and positive regulation of miRNA transcription. Located in nucleus. Expressed in head muscle; intestine; linker cell; somatic nervous system; and tail. Is an ortholog of several human genes including HOXA9 (homeobox A9); HOXB9 (homeobox B9); and HOXC10 (homeobox C10).
Enables transcription coactivator binding activity. Involved in regulation of asymmetric cell division. Located in nucleus. Expressed in several structures, including TL.aa; TL.pa; TR.aa; TR.pa; and hypodermal cell.