srlf-1

Caenorhabditis elegans

Enriched in several structures, including ciliated neurons; egg-laying apparatus; hypodermis; interfacial epithelial cell; and somatic nervous system based on Chronogram; proteomic; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including myrf-1; nuo-6; and htz-1 based on proteomic; microarray; and RNA-seq studies. Is affected by twenty-one chemicals including rotenone; mianserin; and D-glucose based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, metal-binding domain; SXP/RAL-2 family protein Ani s 5-like, cation-binding domain; and SXP/RAL-2-related.

nlp-23

Caenorhabditis elegans

Predicted to be involved in neuropeptide signaling pathway. Expressed in hypodermis and tail.

nlp-30

Caenorhabditis elegans

Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in hypodermis.

nlp-31

Caenorhabditis elegans

Enables double-stranded DNA binding activity. Involved in defense response to Gram-negative bacterium; defense response to fungus; and killing of cells of another organism. Predicted to be located in extracellular region. Expressed in hypodermis.

nlp-27

Caenorhabditis elegans

Involved in defense response to Gram-negative bacterium. Predicted to be located in membrane. Expressed in ASI; head neurons; hypodermis; intestine; and spermatheca.

nlp-18

Caenorhabditis elegans

Predicted to be involved in neuropeptide signaling pathway. Expressed in intestine; neurons; rectal gland cell; and spermatheca.

nlp-21

Caenorhabditis elegans

Predicted to be involved in neuropeptide signaling pathway. Expressed in body wall musculature; dorsal nerve cord; intestine; and neurons.

unc-77

Caenorhabditis elegans

Enables monoatomic cation channel activity. Involved in positive regulation of GABAergic synaptic transmission; positive regulation of cholinergic synaptic transmission; and positive regulation of locomotion. Located in axon. Expressed in cholinergic neurons; nerve ring; pharyngeal neurons; and tail ganglion. Used to study congenital limbs-face contractures-hypotonia-developmental delay syndrome. Human ortholog(s) of this gene implicated in congenital limbs-face contractures-hypotonia-developmental delay syndrome. Is an ortholog of human NALCN (sodium leak channel, non-selective).

nlp-4

Caenorhabditis elegans

Predicted to be located in cell surface.

mir-77

Caenorhabditis elegans

Is affected by several genes including prg-1; hrpk-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. Used to study Parkinson's disease.