myrf-2

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and protein autoprocessing. Predicted to be located in endoplasmic reticulum membrane and nucleus. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; and eye disease (multiple). Is an ortholog of human MYRF (myelin regulatory factor) and MYRFL (myelin regulatory factor like).

myrf-1

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in ecdysis, collagen and cuticulin-based cuticle and nematode larval development. Located in basal part of cell and endoplasmic reticulum. Expressed in several structures, including ciliated neurons; excretory duct; gonad; pharyngeal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; and eye disease (multiple). Is an ortholog of human MYRFL (myelin regulatory factor like).

Y71F9AL.9

Caenorhabditis elegans

Enriched in anal depressor muscle; germ line; hermaphrodite distal tip cell; intestine; and male distal tip cell based on proteomic; Chronogram; and single-cell RNA-seq studies. Is affected by several genes including myrf-1; myrf-2; and mut-16 based on microarray; RNA-seq; proteomic; and tiling array studies. Is affected by nine chemicals including silicon dioxide nanoparticle; paraquat; and Cisplatin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SPATS2-like; UBA-like superfamily; and Phosphorylation site. Is an ortholog of human SPATS2L (spermatogenesis associated serine rich 2 like). Human SPATS2L enables RNA binding activity.

F44E5.1

Caenorhabditis elegans

Enriched in anchor cell; germ line; muscle cell; neurons; and retrovesicular ganglion based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including myrf-1; nuo-6; and mut-16 based on RNA-seq and proteomic studies. Is affected by seven chemicals including rotenone; D-glucose; and rifampin based on RNA-seq and microarray studies.

Y43F8B.1

Caenorhabditis elegans

Enriched in head mesodermal cell; motor neurons; muscle cell; and pharyngeal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including myrf-1; cyd-1; and nuo-6 based on proteomic; RNA-seq; and microarray studies. Is affected by sixteen chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies.

D1065.3

Caenorhabditis elegans

Enriched in ADLL; PDEL; muscle cell; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyc-1; myrf-1; and mut-16 based on microarray; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies.

T23B5.3

Caenorhabditis elegans

Enriched in several structures, including XXX cell; enteric muscle; germ line; neurons; and uv3 based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including myrf-1; atf-7; and atp-2 based on RNA-seq; microarray; and proteomic studies. Is affected by seven chemicals including hydrogen sulfide; Zidovudine; and silicon dioxide nanoparticle based on microarray and RNA-seq studies.

T24B8.3

Caenorhabditis elegans

Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppappa; ABalpppappp; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including cyc-1; myrf-1; and swsn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; bisphenol A; and bisphenol S based on RNA-seq; microarray; and proteomic studies.

nspg-13

Caenorhabditis elegans

Enriched in several structures, including AFD; germ line; head mesodermal cell; intestine; and rectum based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including cyc-1; hyl-2; and myrf-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; Zidovudine; and Psoralens based on microarray and RNA-seq studies.

ccg-1

Caenorhabditis elegans

Enriched in several structures, including DD neuron; GLR; body wall musculature; coelomocyte; and enteric muscle based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including myrf-1; nuo-6; and ztf-11 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including aldicarb; rotenone; and D-glucose based on microarray and RNA-seq studies.