mua-6

Caenorhabditis elegans

Predicted to be a structural constituent of cytoskeleton. Involved in cell-cell adhesion. Located in hemidesmosome. Expressed in hypodermis; touch receptor neurons; uterus; and ventral cord neurons. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2).

F56B3.4

Caenorhabditis elegans

Predicted to be involved in transcription by RNA polymerase II. Is an ortholog of human RPAP1 (RNA polymerase II associated protein 1).

elof-1

Caenorhabditis elegans

Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Located in nucleolus. Is an ortholog of human ELOF1 (elongation factor 1).

ama-1

Caenorhabditis elegans

Contributes to RNA polymerase II activity. Involved in embryo development; gastrulation; and mRNA transcription by RNA polymerase II. Located in chromosome and nuclear body. Part of euchromatin. Is an ortholog of human POLR2A (RNA polymerase II subunit A).

mage-1

Caenorhabditis elegans

Expressed in hypodermis.

rpb-11

Caenorhabditis elegans

Predicted to enable protein dimerization activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2J (RNA polymerase II subunit J); POLR2J2 (RNA polymerase II subunit J2); and POLR2J3 (RNA polymerase II subunit J3).

fcp-1

Caenorhabditis elegans

Enables RNA polymerase II CTD heptapeptide repeat phosphatase activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human CTDP1 (CTD phosphatase subunit 1).

pafo-1

Caenorhabditis elegans

Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Located in nucleus. Is an ortholog of human PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component).

ceh-1

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in DVC; lateral ganglion; and seam cell. Is an ortholog of human NKX1-1 (NK1 homeobox 1) and NKX1-2 (NK1 homeobox 2).

ceh-54

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in neurons. Is an ortholog of several human genes including ESX1 (ESX homeobox 1); RHOXF1 (Rhox homeobox family member 1); and RHOXF2 (Rhox homeobox family member 2).