sumv-1

Caenorhabditis elegans

Located in cytoplasm; neuron projection; and nucleus. Expressed in hypodermis and neurons. Is an ortholog of human INO80D (INO80 complex subunit D).

mys-2

Caenorhabditis elegans

Predicted to enable chromatin binding activity; histone H4K16 acetyltransferase activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of MSL complex; NSL complex; and NuA4 histone acetyltransferase complex. Expressed in germ line. Human ortholog(s) of this gene implicated in breast cancer and clear cell renal cell carcinoma. Is an ortholog of human KAT8 (lysine acetyltransferase 8).

sumv-2

Caenorhabditis elegans

Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of NSL complex. Is an ortholog of human KANSL3 (KAT8 regulatory NSL complex subunit 3).

mau-6

Caenorhabditis elegans

let-6

Caenorhabditis elegans

Acts upstream of or within nematode larval development.

amo-6

Caenorhabditis elegans

cps-6

Caenorhabditis elegans

Enables endonuclease activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Located in mitochondrial intermembrane space. Is an ortholog of human ENDOG (endonuclease G).

Y57G11C.3

Caenorhabditis elegans

Predicted to enable 6-phosphogluconolactonase activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Located in nucleus. Expressed in germ cell. Is an ortholog of human PGLS (6-phosphogluconolactonase).

glb-6

Caenorhabditis elegans

Enables heme binding activity; iron ion binding activity; and oxygen binding activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in neurons and somatic nervous system.

dpy-6

Caenorhabditis elegans

Enables calmodulin binding activity.