Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of NSL complex. Is an ortholog of human KANSL3 (KAT8 regulatory NSL complex subunit 3).
Predicted to enable chromatin binding activity; histone H4K16 acetyltransferase activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of MSL complex; NSL complex; and NuA4 histone acetyltransferase complex. Expressed in germ line. Human ortholog(s) of this gene implicated in breast cancer and clear cell renal cell carcinoma. Is an ortholog of human KAT8 (lysine acetyltransferase 8).
Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in L-leucine catabolic process and ketone body biosynthetic process. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).