cogc-3

Caenorhabditis elegans

Involved in gonad morphogenesis and regulation of cell migration. Located in Golgi apparatus and endoplasmic reticulum. Expressed in intestine; pharynx; seam cell; and vulva. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Is an ortholog of human COG3 (component of oligomeric golgi complex 3).

mig-20

Caenorhabditis elegans

mig-12

Caenorhabditis elegans

mel-29

Caenorhabditis elegans

mig-4

Caenorhabditis elegans

mig-6

Caenorhabditis elegans

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in several processes, including anatomical structure morphogenesis; distal tip cell migration; and nematode larval development. Located in basement membrane. Expressed in several structures, including CAN; GLR; basal lamina; enteric muscle; and somatic gonad precursor. Is an ortholog of human PAPLN (papilin, proteoglycan like sulfated glycoprotein).

mig-23

Caenorhabditis elegans

Enables ADP phosphatase activity; GDP phosphatase activity; and UDP phosphatase activity. Involved in several processes, including gonad morphogenesis; positive regulation of protein glycosylation; and ribonucleoside diphosphate catabolic process. Located in cytoplasm. Expressed in head and tail. Is an ortholog of human ENTPD4 (ectonucleoside triphosphate diphosphohydrolase 4) and ENTPD7 (ectonucleoside triphosphate diphosphohydrolase 7).

snap-29

Caenorhabditis elegans

Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in intracellular protein transmembrane transport; ovulation; and secretion. Located in apical plasma membrane and recycling endosome. Expressed in several structures, including coelomocyte; excretory canal; gland cell; hermaphrodite somatic gonadal cell; and vulva. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in CEDNIK syndrome. Is an ortholog of human SNAP29 (synaptosome associated protein 29).

mig-17

Caenorhabditis elegans

Enables metallopeptidase activity. Involved in several processes, including gonad morphogenesis; protein processing; and regulation of distal tip cell migration. Located in basement membrane and extracellular space. Expressed in several structures, including body wall musculature; gonad; head; intestine; and ventral nerve cord.

daf-29

Caenorhabditis elegans