pag-1

Caenorhabditis elegans

mec-17

Caenorhabditis elegans

Enables tubulin N-acetyltransferase activity. Involved in mechanoreceptor differentiation and thigmotaxis. Predicted to be located in microtubule. Expressed in touch receptor neurons. Used to study neurodegenerative disease. Is an ortholog of human ATAT1 (alpha tubulin acetyltransferase 1).

mec-5

Caenorhabditis elegans

Predicted to be an extracellular matrix structural constituent. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Located in extracellular matrix. Expressed in head; hypodermis; muscle cell; tail; and touch receptor neurons.

mec-15

Caenorhabditis elegans

Involved in several processes, including positive regulation of GABAergic synaptic transmission; positive regulation of multicellular organismal process; and response to mechanical stimulus. Located in perikaryon. Expressed in neurons and spermatheca. Is an ortholog of human FBXW9 (F-box and WD repeat domain containing 9).

mec-14

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus.

mec-1

Caenorhabditis elegans

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in detection of mechanical stimulus involved in sensory perception of touch; extracellular structure organization; and mechanosensory behavior. Predicted to be located in extracellular space. Expressed in PVT; cholinergic neurons; intestinal muscle; and touch receptor neurons.

such-7

Caenorhabditis elegans

mec-18

Caenorhabditis elegans

Predicted to enable CoA-ligase activity. Involved in detection of mechanical stimulus involved in sensory perception of touch and mechanosensory behavior. Located in neuron projection and neuronal cell body. Expressed in PLML; PLMR; and touch receptor neurons.

mec-9

Caenorhabditis elegans

Predicted to enable calcium ion binding activity and serine-type endopeptidase inhibitor activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Predicted to be located in extracellular region. Expressed in PVDL; PVDR; head neurons; touch receptor neurons; and ventral cord neurons.

alr-1

Caenorhabditis elegans

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including epidermis morphogenesis; positive regulation of transcription by RNA polymerase II; and sensory perception of touch. Located in nucleus. Expressed in several structures, including anterior hypodermis; neurons; pseudocoelom; socket cell; and somatic nervous system. Used to study non-syndromic X-linked intellectual disability 1. Human ortholog(s) of this gene implicated in several diseases, including X-linked lissencephaly 2; X-linked recessive disease (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human ALX4 (ALX homeobox 4) and ARX (aristaless related homeobox).