Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Involved in gonad development; nematode larval development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including excretory cell; gonad; pharynx; tail precursor cell; and vulva. Used to study alcohol use disorder and cancer. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome (multiple); carcinoma (multiple); and pre-eclampsia. Is an ortholog of human ARID1A (AT-rich interaction domain 1A).
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Is an ortholog of human PFDN4 (prefoldin subunit 4).