Predicted to enable leucine-tRNA ligase activity. Predicted to be involved in leucyl-tRNA aminoacylation and mitochondrial translation. Predicted to be located in mitochondrion. Expressed in body wall musculature; intestine; and neurons. Used to study Perrault syndrome. Human ortholog(s) of this gene implicated in Perrault syndrome. Is an ortholog of human LARS2 (leucyl-tRNA synthetase 2, mitochondrial).
Predicted to enable leucine-tRNA ligase activity. Involved in positive regulation of protein phosphorylation and translation. Human ortholog(s) of this gene implicated in infantile liver failure syndrome 1. Is an ortholog of human LARS1 (leucyl-tRNA synthetase 1).