Bma-lon-8

Brugia malayi

Is an ortholog of C. elegans lon-8. In C. elegans, lon-8 is involved in nematode male tail tip morphogenesis and regulation of growth.

Bm5115

Brugia malayi

Is predicted to encode a protein with the following domains: ATP-dependent protease La (LON) substrate-binding domain; PUA-like superfamily; Lon protease, N-terminal domain superfamily; Yippee zinc-binding/DNA-binding /Mis18, centromere assembly; Yippee/Mis18/Cereblon; and Lon protease, N-terminal domain. Is an ortholog of C. elegans M18.6.

Bm7561

Brugia malayi

Predicted to be a structural constituent of cuticle. Is an ortholog of C. elegans lon-3 and rol-6. In C. elegans, lon-3 is involved in body morphogenesis and regulation of growth.

Bma-lon-1

Brugia malayi

Is predicted to encode a protein with the following domains: Cysteine-rich secretory protein family; CAP superfamily; CAP domain; and Cysteine-rich secretory protein-related. Is an ortholog of C. elegans lon-1. In C. elegans, lon-1 is involved in several processes, including negative regulation of BMP signaling pathway; negative regulation of DNA endoreduplication; and positive regulation of growth rate.

Bm2670

Brugia malayi

Predicted to be involved in regulation of signal transduction. Predicted to be located in collagen-containing extracellular matrix and plasma membrane. Is an ortholog of O. volvulus Ovo-lon-2.