hbl-1

Caenorhabditis elegans

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and nematode larval development. Located in nucleus. Expressed in several structures, including body wall musculature; germ line; hypodermis; neurons; and ventral nerve cord.

let-57

Caenorhabditis elegans

ZK546.2

Caenorhabditis elegans

Predicted to be located in cytoplasm. Is an ortholog of human LRRC57 (leucine rich repeat containing 57).

msp-57

Caenorhabditis elegans

Expressed in gonad; oocyte; and sperm.

H40L08.3

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Is an ortholog of human CFAP57 (cilia and flagella associated protein 57).

F38H4.16

Caenorhabditis elegans

Is affected by lin-14 and lin-4 based on microarray studies.

unc-57

Caenorhabditis elegans

Involved in clathrin-dependent endocytosis and necroptotic process. Located in neuromuscular junction. Expressed in several structures, including coelomocyte; head; hermaphrodite gonad; intestine; and muscle cell. Human ortholog(s) of this gene implicated in acute myeloid leukemia and high grade glioma. Is an ortholog of human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2); SH3GL2 (SH3 domain containing GRB2 like 2, endophilin A1); and SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3).

T12B5.18

Caenorhabditis elegans

Is affected by sir-2.1; lin-14; and lin-4 based on microarray studies.

mir-57

Caenorhabditis elegans

Expressed in several structures, including P11; P12; body wall musculature; hypodermis; and tail spike.

suv-2

Caenorhabditis elegans