Bm3614

Brugia malayi

Is predicted to encode a protein with the following domains: PDZ domain; Leucine-rich repeat; Leucine-rich repeat, typical subtype; Leucine rich repeat; Leucine-rich repeat domain superfamily; and PDZ superfamily. Is an ortholog of C. elegans let-413. In C. elegans, let-413 is involved in several processes, including adherens junction assembly; embryonic digestive tract morphogenesis; and maintenance of epithelial cell apical/basal polarity.

Bm8058

Brugia malayi

Is predicted to encode a protein with the following domains: Protein phosphatase 2C; PPM-type phosphatase domain; Leucine-rich repeat; Leucine-rich repeat, typical subtype; PPM-type phosphatase domain superfamily; Leucine rich repeat; and Leucine-rich repeat domain superfamily. Is an ortholog of C. elegans let-413; lrch-1; and phlp-2. In C. elegans, let-413 is involved in several processes, including adherens junction assembly; embryonic digestive tract morphogenesis; and maintenance of epithelial cell apical/basal polarity.

Bma-lin-33

Brugia malayi

Is an ortholog of C. elegans lin-33.

Bma-lin-25

Brugia malayi

Predicted to be part of mediator complex. Is an ortholog of C. elegans lin-25. In C. elegans, lin-25 is involved in defense response to Gram-positive bacterium and vulval development.

Bm5625

Brugia malayi

Predicted to be involved in molybdopterin cofactor biosynthetic process. Is an ortholog of C. elegans lin-46 and moc-1. In C. elegans, lin-46 is involved in regulation of development, heterochronic.

Bma-lin-32

Brugia malayi

Predicted to enable protein dimerization activity. Is an ortholog of C. elegans lin-32. In C. elegans, lin-32 is involved in several processes, including negative regulation of gliogenesis; nematode male tail tip morphogenesis; and neurogenesis.

Bma-lin-11

Brugia malayi

Predicted to enable DNA binding activity. Is an ortholog of C. elegans lin-11. In C. elegans, lin-11 is involved in several processes, including axonal fasciculation; egg-laying behavior; and positive regulation of vulval development.

Bma-lin-22

Brugia malayi

Predicted to enable protein dimerization activity. Is an ortholog of C. elegans lin-22. In C. elegans, lin-22 is involved in anterior/posterior pattern specification; negative regulation of gene expression; and nematode male tail tip morphogenesis.

Bma-lin-54

Brugia malayi

Is predicted to encode a protein with the following domains: CRC domain; Tesmin/TSO1-like CXC domain; Tesmin/TSO1-like CXC domain, cysteine-rich domain; and Lin-54 family. Is an ortholog of C. elegans lin-54.

Bm5252

Brugia malayi

Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans lin-61 and mbtr-1. In C. elegans, lin-61 is involved in vulval development.