Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of cell cycle; negative regulation of vulval development; and positive regulation of brood size. Located in nucleus. Expressed in several structures, including head and tail. Used to study intellectual disability. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); high grade glioma (multiple); and urinary system cancer (multiple). Is an ortholog of human RBL1 (RB transcriptional corepressor like 1) and RBL2 (RB transcriptional corepressor like 2).
Is affected by several genes including unc-25; alg-1; and lin-35 based on RNA-seq and microarray studies. Is affected by bortezomib; Sirolimus; and allantoin based on RNA-seq and microarray studies.
Enriched in RIAL and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including etr-1; dpl-1; and lin-35 based on RNA-seq and microarray studies.