Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including clk-1; lin-39; and mir-34 based on RNA-seq and microarray studies.
Involved in several processes, including determination of adult lifespan; negative regulation of autophagy; and response to stress. Expressed in excretory canal; hypodermis; neurons; somatic nervous system; and vulval precursor cell.
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus.
Predicted to enable guanylate cyclase activity. Involved in chemosensory behavior and sensory perception of bitter taste. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)).