Predicted to be involved in endoplasmic reticulum organization. Predicted to be located in endoplasmic reticulum. Is an ortholog of human PCNX2 (pecanex 2) and PCNX3 (pecanex 3).
Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is an ortholog of human POLR3G (RNA polymerase III subunit G) and POLR3GL (RNA polymerase III subunit GL).
Predicted to enable chromatin binding activity; histone H4K16 acetyltransferase activity; and transcription coregulator activity. Involved in cell fate specification; maintenance of left/right asymmetry; and positive regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of MSL complex; NSL complex; and NuA4 histone acetyltransferase complex.
Predicted to enable dephospho-CoA kinase activity. Predicted to be involved in coenzyme A biosynthetic process. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III; neurodegeneration with brain iron accumulation 6; and pontocerebellar hypoplasia type 12. Is an ortholog of human COASY (Coenzyme A synthase).
Predicted to enable endopeptidase activity. Involved in several processes, including apical protein localization; egg-laying behavior; and regulation of signal transduction. Located in perinuclear region of cytoplasm. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 3; Alzheimer's disease 4; Pick's disease; dilated cardiomyopathy (multiple); and hidradenitis suppurativa. Is an ortholog of human PSEN1 (presenilin 1) and PSEN2 (presenilin 2).