mek-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein serine/threonine/tyrosine kinase activity and scaffold protein binding activity. Involved in defense response to Gram-positive bacterium; intracellular signaling cassette; and vulval development. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); cardiofaciocutaneous syndrome 3; and cardiofaciocutaneous syndrome 4. Is an ortholog of human MAP2K1 (mitogen-activated protein kinase kinase 1) and MAP2K2 (mitogen-activated protein kinase kinase 2).