laf-1

Caenorhabditis elegans

Enables RNA strand annealing activity; identical protein binding activity; and molecular condensate scaffold activity. Involved in several processes, including masculinization of hermaphroditic germ-line; positive regulation of embryonic development; and positive regulation of fertilization. Located in P granule. Expressed in germ line. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and syndromic X-linked intellectual disability. Is an ortholog of human DDX3X (DEAD-box helicase 3 X-linked) and DDX3Y (DEAD-box helicase 3 Y-linked).

vbh-1

Caenorhabditis elegans

Predicted to enable RNA helicase activity and mRNA binding activity. Involved in developmental process involved in reproduction; positive regulation of embryonic development; and positive regulation of fertilization. Located in P granule and cytoplasmic stress granule. Expressed in several structures, including Z2; Z3; germ cell; somatic cell; and in male. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and syndromic X-linked intellectual disability. Is an ortholog of human DDX3X (DEAD-box helicase 3 X-linked).