klp-16

Caenorhabditis elegans

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in chromosome segregation. Located in neuronal cell body. Expressed in several structures, including ABa; EMS; Psub2; germ line; and head.

klp-17

Caenorhabditis elegans

Predicted to enable microtubule binding activity. Involved in chromosome segregation. Predicted to be located in microtubule cytoskeleton. Expressed in germ line and sperm.

klp-3

Caenorhabditis elegans

Predicted to enable microtubule binding activity. Involved in chromosome separation. Predicted to be located in microtubule cytoskeleton. Expressed in marginal cell. Is an ortholog of human KIFC3 (kinesin family member C3).

klp-18

Caenorhabditis elegans

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic spindle assembly. Located in cell cortex; microtubule; and spindle pole. Expressed in Z2; Z3; and germ line. Is an ortholog of human KIF15 (kinesin family member 15).

klp-4

Caenorhabditis elegans

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport and microtubule-based movement. Located in axon; cytoplasmic microtubule; and neuronal cell body. Expressed in distal tip cell; dorsal nerve cord; head; and ventral nerve cord. Is an ortholog of human KIF13A (kinesin family member 13A) and KIF13B (kinesin family member 13B).

klp-20

Caenorhabditis elegans

Enables microtubule motor activity. Involved in microtubule-based movement. Part of axonemal heterotrimeric kinesin-II complex. Expressed in ciliated neurons; distal tip cell; head; touch receptor neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in silicosis. Is an ortholog of human KIF3A (kinesin family member 3A).

klp-19

Caenorhabditis elegans

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic chromosome condensation and meiotic spindle midzone assembly. Located in condensed nuclear chromosome; nucleoplasm; and spindle. Expressed in germ line. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 100. Is an ortholog of human KIF4A (kinesin family member 4A).

klp-11

Caenorhabditis elegans

Enables microtubule motor activity. Involved in microtubule-based movement. Part of axonemal heterotrimeric kinesin-II complex. Expressed in amphid neurons; dorsal nerve cord; inner labial neurons; phasmid neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in retinitis pigmentosa 89. Is an ortholog of human KIF3B (kinesin family member 3B) and KIF3C (kinesin family member 3C).

klp-6

Caenorhabditis elegans

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport and microtubule-based movement. Located in neuronal cell body and plasma membrane bounded cell projection. Expressed in ciliated neurons; head; tail; and in male. Used to study autosomal dominant polycystic kidney disease. Is an ortholog of human KIF28P (kinesin family member 28, pseudogene).

osm-3

Caenorhabditis elegans

Enables plus-end-directed microtubule motor activity. Involved in several processes, including cilium organization; dauer entry; and regulation of non-motile cilium assembly. Located in neuronal cell body; perinuclear region of cytoplasm; and plasma membrane bounded cell projection. Part of kinesin complex. Expressed in ciliated neurons. Is an ortholog of human KIF17 (kinesin family member 17).