Bm3917

Brugia malayi

Predicted to enable calcium ion binding activity; metalloendopeptidase activity; and zinc ion binding activity. Predicted to be involved in proteolysis. Is an ortholog of C. elegans nrx-1; itx-1; and hch-1. In C. elegans, hch-1 is involved in hatching and neuron migration.

Bm12362

Brugia malayi

Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: EGF-like domain; Laminin G domain; Growth factor receptor cysteine-rich domain superfamily; Fibrinogen-like, C-terminal; and Concanavalin A-like lectin/glucanase domain superfamily. Is an ortholog of O. volvulus Ovo-itx-1.