F39E9.1

Caenorhabditis elegans

Enriched in head mesodermal cell; intestine; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hyl-2; hyl-1; and swsn-2.2 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Heme; D-glucopyranose; and multi-walled carbon nanotube based on microarray and RNA-seq studies.

C50F7.5

Caenorhabditis elegans

Enriched in head mesodermal cell; intestine; neurons; and in male based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including cyc-1; hyl-2; and hyl-1 based on microarray; RNA-seq; and tiling array studies. Is affected by forty-seven chemicals including 1-methylnicotinamide; rotenone; and Tunicamycin based on RNA-seq and microarray studies.

F25B3.5

Caenorhabditis elegans

Enriched in several structures, including ABplpppaaa; coelomocyte; ganglia; gonad; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyc-1; hyl-2; and hyl-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; 4-bromodiphenyl ether; and levamisole based on microarray and RNA-seq studies.

hyl-2

Caenorhabditis elegans

Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Expressed in head; hypodermis; intestine; tail; and terminal bulb. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 9. Is an ortholog of human CERS6 (ceramide synthase 6).

K04F1.9

Caenorhabditis elegans

Enriched in cephalic sheath cell; dopaminergic neurons; germ line; hypodermis; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hyl-2; hyl-1; and nuo-6 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-eight chemicals including methylmercuric chloride; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies.

C01G10.4

Caenorhabditis elegans

Enriched in interfacial epithelial cell; male-specific anatomical entity; and pharyngeal muscle cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including cyc-1; hyl-2; and hyl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including methylmercuric chloride; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies.

T08G5.14

Caenorhabditis elegans

Enriched in AWBL based on single-cell RNA-seq studies. Is affected by several genes including hyl-1; ints-8; and alg-1 based on RNA-seq and microarray studies.

Y46D2A.1

Caenorhabditis elegans

Enriched in muscle cell; neurons; and rectal valve cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including hyl-2; hyl-1; and swsn-2.2 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including D-glucose; Zidovudine; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein.

clec-173

Caenorhabditis elegans

Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including hyl-2; hyl-1; and nuo-6 based on RNA-seq; microarray; and proteomic studies. Is affected by sixteen chemicals including Tunicamycin; mianserin; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin-like; and C-type lectin fold.

hyl-1

Caenorhabditis elegans

Predicted to enable sphingosine N-acyltransferase activity. Involved in regulation of locomotion. Located in axon. Expressed in motor neurons. Is an ortholog of human CERS6 (ceramide synthase 6).