hsp-16.11

Caenorhabditis elegans

Predicted to enable unfolded protein binding activity. Involved in endoplasmic reticulum unfolded protein response.

hsp-16.48

Caenorhabditis elegans

Predicted to enable unfolded protein binding activity. Involved in determination of adult lifespan and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including coelomocyte; enteric muscle; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A).

hsp-16.1

Caenorhabditis elegans

Predicted to enable unfolded protein binding activity. Involved in defense response to Gram-negative bacterium and response to heat. Located in Golgi medial cisterna. Expressed in several structures, including coelomocyte; enteric muscle; intestine; pharynx; and ventral nerve cord.

hsp-16.2

Caenorhabditis elegans

Predicted to enable unfolded protein binding activity. Involved in response to heat. Located in cytoplasm. Expressed in several structures, including coelomocyte; enteric muscle; gonad; somatic nervous system; and spermatid.

hsp-16.41

Caenorhabditis elegans

Predicted to enable unfolded protein binding activity. Involved in defense response to Gram-negative bacterium and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including alimentary muscle; coelomocyte; intestine; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A).

hsp-16.49

Caenorhabditis elegans

Predicted to enable unfolded protein binding activity. Involved in endoplasmic reticulum unfolded protein response. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A).

hsp-12.6

Caenorhabditis elegans

Enables identical protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in cytoplasm. Expressed in hypodermis; intestine; muscle cell; and spermatid. Human ortholog(s) of this gene implicated in cataract (multiple); dilated cardiomyopathy 1II; and myofibrillar myopathy (multiple). Is an ortholog of human CRYAA (crystallin alpha A); CRYAB (crystallin alpha B); and HSPB6 (heat shock protein family B (small) member 6).

hsp-6

Caenorhabditis elegans

Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Involved in mitochondrial unfolded protein response. Located in mitochondrion. Expressed in muscle cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; autosomal dominant sideroblastic anemia 4; and rheumatoid arthritis. Is an ortholog of human HSPA9 (heat shock protein family A (Hsp70) member 9).

Y71A12B.23

Caenorhabditis elegans

Enriched in XXXL and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including swsn-1; mut-16; and hsp-6 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; antimycin; and Doxycycline based on RNA-seq studies.

21ur-2624

Caenorhabditis elegans

Is affected by several genes including numr-2; numr-1; and hsp-6 based on RNA-seq studies.