Predicted to enable damaged DNA binding activity. Involved in DNA damage response and telomere maintenance via telomerase. Predicted to be located in nucleus. Predicted to be part of checkpoint clamp complex. Is an ortholog of human RAD1 (RAD1 checkpoint DNA exonuclease).
Predicted to enable chromatin binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA damage checkpoint signaling; DNA repair; and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Is an ortholog of human RAD17 (RAD17 checkpoint clamp loader component).
Involved in several processes, including DNA damage response; determination of adult lifespan; and telomere maintenance. Located in germ cell nucleus. Part of chromatin. Expressed in germ line. Is an ortholog of human HUS1B (HUS1 checkpoint clamp component B).