zipt-7.1

Caenorhabditis elegans

Enables zinc ion transmembrane transporter activity. Involved in several processes, including intracellular zinc ion homeostasis; positive regulation of brood size; and regulation of reproductive process. Located in membrane. Expressed in hypodermis; neurons; spermatocyte; ventral nerve cord; and vulva.

atg-4.1

Caenorhabditis elegans

Enables cysteine-type endopeptidase activity. Involved in aggrephagy and protein processing. Located in cytoplasm. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; head muscle; and somatic nervous system. Is an ortholog of human ATG4A (autophagy related 4A cysteine peptidase).

frm-2

Caenorhabditis elegans

Predicted to enable cytoskeletal protein binding activity. Predicted to be involved in actomyosin structure organization. Predicted to be located in cytoskeleton. Expressed in intestinal cell; pharyngeal epithelial cell; and sensory neurons. Is an ortholog of human EPB41L4B (erythrocyte membrane protein band 4.1 like 4B) and EPB41L5 (erythrocyte membrane protein band 4.1 like 5).

phy-4

Caenorhabditis elegans

Contributes to peptidyl-proline 4-dioxygenase activity. Part of procollagen-proline 4-dioxygenase complex. Expressed in excretory duct; pharyngeal gland cell; and pharyngeal-intestinal valve.

frm-1

Caenorhabditis elegans

Predicted to enable actin binding activity and structural molecule activity. Predicted to be involved in actomyosin structure organization. Located in plasma membrane. Expressed in several structures, including intestine and pharynx. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 11; esophagus squamous cell carcinoma; and meningioma. Is an ortholog of human EPB41L1 (erythrocyte membrane protein band 4.1 like 1) and EPB41L3 (erythrocyte membrane protein band 4.1 like 3).

rrn-4.1

Caenorhabditis elegans

ptp-1

Caenorhabditis elegans

Predicted to enable protein tyrosine phosphatase activity. Located in sarcoplasmic reticulum. Expressed in muscle cell; nerve ring; neurons; pharyngeal nervous system; and ventral nerve cord. Is an ortholog of human PTPN3 (protein tyrosine phosphatase non-receptor type 3) and PTPN4 (protein tyrosine phosphatase non-receptor type 4).

frm-5.1

Caenorhabditis elegans

Predicted to enable kinase activity. Is an ortholog of human FRMPD2 (FERM and PDZ domain containing 2).

atg-4.2

Caenorhabditis elegans

Enables cysteine-type endopeptidase activity. Predicted to be involved in macroautophagy and protein processing. Predicted to be located in cytoplasm. Expressed in embryonic cell; gonad; and oocyte. Is an ortholog of human ATG4D (autophagy related 4D cysteine peptidase).

frm-10

Caenorhabditis elegans

Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be located in plasma membrane. Is an ortholog of human FRMD8 (FERM domain containing 8).