Bma-him-4

Brugia malayi

Predicted to enable calcium ion binding activity. Is an ortholog of C. elegans him-4. In C. elegans, him-4 is involved in basement membrane disassembly.

Bma-him-10

Brugia malayi

Predicted to be located in kinetochore. Predicted to be part of Ndc80 complex. Is an ortholog of C. elegans him-10. In C. elegans, him-10 is involved in kinetochore organization; mitotic spindle organization; and nuclear chromosome segregation.

Bma-him-1

Brugia malayi

Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in chromosome organization. Predicted to be located in chromosome. Is an ortholog of C. elegans him-1. In C. elegans, him-1 is involved in chromosome segregation; embryo development; and response to radiation.

Bma-him-14

Brugia malayi

Predicted to enable ATP binding activity; ATP-dependent DNA damage sensor activity; and mismatched DNA binding activity. Predicted to be involved in mismatch repair. Is an ortholog of C. elegans him-14. In C. elegans, him-14 is involved in chiasma assembly; embryo development; and resolution of meiotic recombination intermediates.

Bma-him-6

Brugia malayi

Predicted to enable 3'-5' DNA helicase activity; ATP binding activity; and nucleic acid binding activity. Predicted to be involved in DNA recombination; DNA repair; and DNA replication. Is an ortholog of C. elegans him-6. In C. elegans, him-6 is involved in several processes, including determination of adult lifespan; meiotic nuclear division; and resolution of DNA recombination intermediates.

Bm10842

Brugia malayi

Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domain: SKP1/BTB/POZ domain superfamily. Is an ortholog of O. volvulus Ovo-him-18.