hda-6

Caenorhabditis elegans

Predicted to enable histone deacetylase activity. Predicted to be involved in epigenetic regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia; and polycystic liver disease. Is an ortholog of human HDAC6 (histone deacetylase 6).

mau-6

Caenorhabditis elegans

let-6

Caenorhabditis elegans

Acts upstream of or within nematode larval development.

amo-6

Caenorhabditis elegans

cps-6

Caenorhabditis elegans

Enables endonuclease activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Located in mitochondrial intermembrane space. Is an ortholog of human ENDOG (endonuclease G).

Y57G11C.3

Caenorhabditis elegans

Predicted to enable 6-phosphogluconolactonase activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Located in nucleus. Expressed in germ cell. Is an ortholog of human PGLS (6-phosphogluconolactonase).

glb-6

Caenorhabditis elegans

Enables heme binding activity; iron ion binding activity; and oxygen binding activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in neurons and somatic nervous system.

dpy-6

Caenorhabditis elegans

Enables calmodulin binding activity.

rax-6

Caenorhabditis elegans

vab-6

Caenorhabditis elegans