Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in cell fate determination; cell migration; and regulation of neuron differentiation. Located in nucleus.
Predicted to be located in mitochondrion. Is an ortholog of several human genes including ARMCX1 (armadillo repeat containing X-linked 1); ARMCX2 (armadillo repeat containing X-linked 2); and ARMCX3 (armadillo repeat containing X-linked 3).
Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including generation of neurons; positive regulation of transcription by RNA polymerase II; and protein localization. Located in cell cortex and nucleus. Expressed in neuroblasts. Human ortholog(s) of this gene implicated in Alzheimer's disease and pre-eclampsia. Is an ortholog of human STOX1 (storkhead box 1).
Enriched in M.vrpaapap; anal depressor muscle; and mu_int_L based on single-cell RNA-seq studies. Is affected by ham-3 and daf-2 based on RNA-seq and microarray studies. Is affected by Colistin based on microarray studies.
Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Is an ortholog of human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2) and PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3).
Involved in dosage compensation by hypoactivation of X chromosome and negative regulation of transcription by RNA polymerase II. Located in nuclear chromosome.
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in Y-linked spermatogenic failure 2; female-restricted syndromic X-linked intellectual disability 99; and non-syndromic X-linked intellectual disability 99. Is an ortholog of human USP24 (ubiquitin specific peptidase 24).