Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including generation of neurons; positive regulation of transcription by RNA polymerase II; and protein localization. Located in cell cortex and nucleus. Expressed in neuroblasts. Human ortholog(s) of this gene implicated in Alzheimer's disease and pre-eclampsia. Is an ortholog of human STOX1 (storkhead box 1).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in cell fate determination; cell migration; and regulation of neuron differentiation. Located in nucleus.
Enriched in M.vrpaapap; anal depressor muscle; and mu_int_L based on single-cell RNA-seq studies. Is affected by ham-3 and daf-2 based on RNA-seq and microarray studies. Is affected by Colistin based on microarray studies.
Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 7. Is an ortholog of human COX6B1 (cytochrome c oxidase subunit 6B1).
Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 16. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2).