glo-3

Caenorhabditis elegans

Involved in gastrulation. Located in gut granule membrane. Expressed in intestine.

pgp-2

Caenorhabditis elegans

Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in gut granule assembly and lipid storage. Located in gut granule membrane. Expressed in AWAL and AWAR. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4).

flu-4

Caenorhabditis elegans

elt-7

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate determination. Located in nucleus. Expressed in E lineage cell.

ges-1

Caenorhabditis elegans

Enables carboxylesterase activity. Involved in cellular catabolic process. Located in peroxisome. Expressed in pharynx. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1).

zipt-2.3

Caenorhabditis elegans

Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Located in gut granule. Expressed in intestinal cell. Is an ortholog of human SLC39A1 (solute carrier family 39 member 1) and SLC39A2 (solute carrier family 39 member 2).

R10E11.6

Caenorhabditis elegans

Enriched in AVK; NSM; VD neuron; anterior hypodermis; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including etr-1; isp-1; and mrps-5 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rifampin; allantoin; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: EF-hand domain pair and Synergin gamma. Is an ortholog of human SYNRG (synergin gamma).

vha-2

Caenorhabditis elegans

Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in programmed cell death and proton transmembrane transport. Predicted to be located in membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Expressed in excretory cell and rectum. Human ortholog(s) of this gene implicated in early-onset epilepsy 3 and thyroid gland carcinoma. Is an ortholog of human ATP6V0C (ATPase H+ transporting V0 subunit c).

zim-2

Caenorhabditis elegans

Predicted to be involved in meiotic chromosome segregation. Located in condensed nuclear chromosome.

vha-3

Caenorhabditis elegans

Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Expressed in excretory cell; hypodermis; and intestinal cell. Human ortholog(s) of this gene implicated in early-onset epilepsy 3 and thyroid gland carcinoma. Is an ortholog of human ATP6V0C (ATPase H+ transporting V0 subunit c).